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doi: 10.3389/fpsyt.2022.813304 90 Lobo-SilvaD.CarricheG

The blend is supplied as a lyophilized powder requiring reconstitution with a sterile diluent (commonly bacteriostatic water) prior to laboratory use

This is supported by data from Jacobson et al., describing higher Tac trough levels with increasing age (105) and our data, since we found a higher rate of slow metabolizers in elderly than in younger patients (106)